Download e-book for kindle: Biochemical Actions of Hormones. Volume 11 by Gerald Litwack

By Gerald Litwack

ISBN-10: 0124528112

ISBN-13: 9780124528116

ISBN-10: 0323151892

ISBN-13: 9780323151894

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Guided by the successes of molecular genetics in elucidating regulatory mechanisms in procaryotes, Tomkins and his co-workers initiated efforts to isolate animal-cell mutants carrying lesions in the cAMP response pathway. , 1973). As illustrated in Fig. 2, a variety of pharmacological agents are available for manipulating metabolism of cAMP or for bypassing the cAMP generation system to activate cAMP-dependent protein kinase directly. This diversity of drugs has proven invaluable in the selection and characterization of mutants affected in different components of the cAMP response system.

Bes. Commun. 96, 1679-1687. , Clark, D. , and Corey, E. J. (1980b). Biochem. Biophys. Bes. Commun. 92, 954-961. , and Sirois, P. (1982). Biochem. Biophys. Bes. Commun. 108, 1531-1537. Samuelsson, B. (1983). In "Advances in Prostaglandin, Thromboxane and Leukotriene Research" (B. Samuelsson,R. ), Vol. 11, pp. 1-26. Raven Press, New York. , and Hammarström, S. (1980). Prostaglandins 19, 645-648. , Murphy, R. C , and Hammarström, S. (1979). Prostoglandins 17, 785-787. Serhan, C. , Goetzl, E. , Dunham, P.

Biol. Chem. 257, 4746-4752. Sha'afi, R. , Molski, T. F. , Naccache, P. H. (1981). Biochem. Biophys. Bes. Commun. 103, 766-773. Showell, H. , Naccache, P. , and Sha'afi, R. (1982). / . Immunol. 128, 811-816. Sirois, P. (1979). Prostaglandins 17, 395-404. , Dahlén, S. , and Sammuelsson, B. (1982). Nature (London) 295, 327-329. , and Uvnäs, B. (1971). Ada Physiol. Scand. 82, 358-374. , and Kikuchi, S. (1981). Eur. J. Pharmacol. 73, 357-361. , Maas, R. , Brash, A. , Roberts, L. , and Oates, J. A. (1982).

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Biochemical Actions of Hormones. Volume 11 by Gerald Litwack

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